Amebiasis is a parasitic infection caused by Entamoeba histolytica. Currently, no approved vaccine is available to prevent amebiasis, although research is ongoing. Prevention primarily relies on proper hygiene, safe drinking water, and sanitation. Treatment options include antiparasitic medications like nitazoxanide, commonly sold under the brand name nizonide 500mg. Nizonide 500mg is effective in managing parasitic infections, including those caused by E. histolytica. To reduce the risk of amebiasis, avoid consuming contaminated food or water, and maintain good hand hygiene. While vaccination development continues, early diagnosis and treatment with medications like Nizonide 500mg remain crucial in controlling the disease.